Peptide Arrays 2013
Edinburgh, UK, September 3 - 4, 2013
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You can download the Final Programme as a PDF.

Invited Speakers

Coffee & Tea / Exhibition / Posters

Tuesday, September 3

09:00 Registration / Coffee & Tea / Exhibition
09:30 Keynote lecture: Application of Micro-array Platforms

Mark Bradley, School of Chemistry, University of Edinburgh
10:30 Coffee & Tea / Exhibition / Posters

Session 2: Methodology
10:45 High content peptide microarrays

Renate Sekul, PepPERPrint
11:10 The use of CLIPS-technology in peptide arrays

Peter Timmermans, Pepscan
11:35 Design of Peptide Arrays - lessons learned

Nicola O'Reilly, CRUK London Research Institute
11:55 Inkjet Technology for Peptide Array Synthesis

Iain McWilliam, Arrayjet
Towards High-complexity and High-quality Peptide Microarrays 
Alexander Nesterov-Müller / Christopher Schirwitz, Karlsruhe Institute of Technology
13:00 Lunch / Exhibition / Session 3: Posters

Session 4: Biophysical & Bioengineering Applications of Peptide Arrays
Bioorganic Nanodots: Principles, Physics and Applications
Gil Rosenman, Tel Aviv University
Electrochemical kinase sensors based on reversible structural transitions in peptidic monolayers
Shlomo Yitzchaik, The Hebrew University, Jerusalem
Coffee & Tea / Exhibition / Posters
Session 5: Post-translational Modification
Peptide Ligand Discovery for Acetyl-lysine Readers
Panagis Filippakopoulos, University of Oxford
The Challenge of Complexity: High-content peptide libraries to display sequence diversity and posttranslational modifications
Ulf Reimer, JPT Peptide Technologies
Application of peptide arrays in the specificity analysis of protein lysine methyltransferases and methyllysine binding domains

Srikanth Kudithipudi, University of Stuttgart
17:30 Close of Day 1

Wednesday, September 4

Session 6: The Interactome
09:00 Selectively Uncoupling EPAC1 from its Regulators: Disrupting Peptides Allow Selectivity in Vascular Cells

Donald Maurice, Queen's University, Kingston, ON
09:30 Using peptide arrays to decipher and target protein-protein interactions in signalling pathways

Pat Kiely, University of Limerick
The SH3 domains of the multi-functional adaptor protein CD2AP recognise the Rab-GEF Rin3 via atypical SH3 binding motifs
Jenny Rouka, University of Oxford
Decyphering the antibodyome – peptide microarrays for routine high throughput seroanalytics
Carsten Grötzinger, Charité, Berlin
10:40 Coffee & Tea / Exhibition / Posters

Session 7: Peptide Arrays in Drug Discovery & Delivery
11:10 Structure activity relationship studies using peptide arrays

Assaf Friedler, The Hebrew University of Jerusalem
11:40 Reverse phase protein arrays

Bryan Serrels, Edinburgh Cancer Research UK Centre
12:10 Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo

Peter Deuss, MRC Laboratory of Molecular Biology, Cambridge
12:30 Lunch / Exhibition / Posters

Session 7: Peptide Arrays in Drug Discovery & Delivery continued
13:30 Drug discovery using cell-free DNA display: CIS display

Walraj Gosal, Isogenica Ltd.
14:00 Peptide array technology identifies p62/SQSTM1 as a new PDE4 binding partner and PKA substrate with implications for interaction partners

Frank Christian, University of Glasgow
14:30 Peptide Vectors for Breaching the Blood-Brain Barrier: New Directions in CNS Drug Delivery

Pankaj Karande, Rensselaer Polytechnic Institute, Troy, NY
15:00 Opportunities for peptidomimetic arrays

Prof. Robert Liskamp, University of Glasgow
15:30 Session 8: Poster Prize sponsored by the Protein & Peptide Science Group of the Royal Society of Chemistry
16:00 Close of Meeting

Panagis Fillipakopoulos, University of Oxford

Dr.Fillipakopoulos's group employs high throughput structural biology techniques in order to study the structural and functional role of BET bromodomains in transcription initiation and the implications of dysfunctional BET bromodomains in disease.

Assaf Friedler, The Hebrew University of Jerusalem, Israel

Prof. Friedler has set up an interdisciplinary platform for the study of protein-protein interactions, encompassing Organic Chemistry, Biophysics, Molecular and Theoretical Biology.

Albert Jeltsch, University of Stuttgart, Germany

Prof. Jeltsch's group works in the field of Molecular Epigenetics, studying the methylation of DNA and histone proteins as well as protein modules that specifically read these modifications. They also investigate the mechanism and specificiy of enzymes involved in epigenetic processes and are engaged in the development of enzyme inhibitors. In Synthetic Biology, thye aim to improve the properties of enzymes and proteins for various applications by rational and evolutionary design and develop artificial gene regulation elements. Prof. Jeltsch is unable to attend and his talk is being given by a colleague, Dr. Srikanth Kudithipudi

Pankaj Karande, Rensselaer Polytechnic Institute , Troy, NY, USA

Prof. Karande’s research programme is focused on engineering peptides as novel drugs, drug carriers and multifunctional biomaterials for medical applications.

Pat Kiely, University of Limerick

Dr. Kiely's research emphasis is on deciphering the localized and transient signalling events which occur in cells during migration. His group uses a series of complimentary and synergistic molecular approaches and novel technologies (including 3-dimensional cell culture models and peptide array technology) to investigate how protein complexes are assembled in signalling pathways during this process.

Robert Liskamp, University of Glasgow

Prof. Liskamp has recently moved to take the Chair of Chemical Biology and Medicinal Chemistry in the School of Chemistry, University of Glasgow. Previosuly he was Head of Medicinal Chemistry and Chemicals Biology in the Department of Pharmaceutical Sciences at the University of Utrecht.

Donald Maurice, Queen's University, Kingston ON, Canada

Prof. Maurice is Director of the Cardiac, Circulatory & Respiratory Research Program. Studies in progress in his laboratory focus on the molecular basis of cyclic nucleotide-mediated effects in vascular tissues

Gil Rosenman, Tel Aviv University, Israel

Prof. Rosenman has developed peptide nanodots that show interesting physics, from ferroelectricity and nonlinear optics to strong luminescence and charge memory. He has created peptide dot arrays with 20nm resolution that can be used for ultradense charge memory devices (flash bioorganic memory).

Bryan Serrels, Edinburgh Cancer Research UK Centre, UK

Dr. Serrels works in the group of Margaret Frame, Science Director of the Edinburgh Cancer Research UK Centre. He uses Reverse Phase Protein Arrays (RPPA) as a high throughput functional proteomics tool for the analysis of pre-clinical and clinical material. The technique is an interesting complement to peptide array technologies.

Shlomo Yitzchaik,Institute of Chemistry and The Nanoscience and Nanotechnology Center, The Hebrew University of Jerusalem, Israel

Prof. Yitzchaik will describe selectivity data in the kinase-promoted phosphorylation of peptidic substrates, either in microarrays (glass or plastic) or electrode-immobilized (gold or nitride) using the serine/threonine kinases PKA, PKC, and CaMK2.