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Prof. Robin Leatherbarrow, Imperial College London.
Robin Leatherbarrow is Chair of Chemical Biology and Head of the Chemical Biology Section within the Chemistry Department. He is one of the leading UK chemical biologists and has been greatly involved in the promotion and development of this new area of chemistry over recent years. His research is concerned with molecular recognition between proteins and their ligands, which involves a multidisciplinary blend of physical and biological sciences, ranging from structural biology, through enzymology to synthetic chemistry. A leading exponent of protein engineering, he was involved at the outset in pioneering work in this area along with Sir Alan Fersht. Since then, he has advanced methods to study ligand binding, particularly concerning enzyme-inhibitor interactions. His work on the study and rational design of enzyme inhibitors has attracted considerable industrial interest from leading pharmaceutical companies. Most of his research efforts involve the application of biophysical or chemical tools to new areas of biology. He has particular interest in peptide synthesis, modern enzymology and developing new enzyme inhibitors. Biological interests include the action of protease enzymes as well as other peptide-modifying enzymes. |
